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br intensities of miR ISH did not correlate
2022-05-30
intensities of miR-182 ISH did not correlate with clinical parameters (Supplemental Figure S2B and data not shown). Therefore, internal normalization was applied through the cancer/benign ratio of miR-182 Polybrene per patient, to reduce potential confounding due to interpatient differences in
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sensitivity analyses using a period of days prior to
2022-05-30
sensitivity analyses using a Lactacystin of 14 days prior to treatment start date to distinguish staging MRI from MRI studies performed in the context of treatment planning. The primary study outcome was initial management for PCa, ie, observation vs definitive therapy. Observation was defined a
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DMOG br We found that long term NSAID use was associated
2022-05-25
We found that long-term NSAID use was associated with a shorter LOS. Our findings are consistent with other studies, which suggest that cancer-related pain (usually associated with advanced metastatic dis-ease especially to the bone) increases the likelihood of patient referral for specialist trea
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br stages during cell cycle progression Walker and
2022-05-23
stages during cell cycle progression (Walker and Assoian, 2005). Sev-eral newer agents have been developed that selectively target one or more CDKs, rather than disrupting the cytoskeleton, to inhibit tumour cell proliferation and some have entered clinical trials (Law et al., 2015). Thus, the
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Hydrodynamic diameter size distribution and
2022-05-23
Hydrodynamic diameter, size distribution and zeta potential of nanoparticles were determined via dynamic light scattering (DLS) (Brookhaven Instrument, USA). Morphology of the nanoparticles was identified by scanning electron microscopy (SEM). The SEM procedure was performed by drying of NPs suspe
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br The PC and PC
2022-05-22
The PC-3 and PC-3-luc cells were cultured at 2 £ 105 cells/well in 12-well cell culture plates, and cultured at 37˚ C and in 5% CO2 for 24 hours. The PC-3 and PC-3-luc cells were harvested and washed 3 times with phosphate-buff-ered saline (PBS). The PC-3 and PC-3-luc cells were resus-pended in 5
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br Corresponding author E mail addresses
2022-05-22
∗ Corresponding author. E-mail addresses: [email protected] (J.E. Felenda), [email protected] (F.C. Stintzing). Belonging to the group of thionins, small, cysteine-rich polypeptides (Bohlmann and Apel, 1991), several VTs occur in mistletoe, which have been designated A1, A2, A3,
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br Introduction br Ovarian cancer is the
2022-05-22
1. Introduction Ovarian cancer is the most aggressive, and the foremost cause of death, of all gynecological cancers [1–3]. The primary factors con-tributing to the poor prognosis and high mortality rate associated with ovarian cancer is a combination of non-specific symptoms and a lack of earl
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br Fig Overexpression of dup in NSCLC cell lines
2022-05-22
Fig. 3. Overexpression of dupα7 in NSCLC cell lines suppresses the in vitro pro-migratory effects of nicotine or NNK. Cell migration in A549 CFTRinh-172 (top) or SK-MES-1 cells (bottom) was determined by the transwell migration assay. (A) Representative confocal images (40X) of the migration rate i
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br Paclitaxel has been used as frontline chemotherapeutic agent
2022-05-20
Paclitaxel has been used as frontline chemotherapeutic agent for breast cancer; however, recent studies have pointed that paclitaxel exacerbate breast cancer metastasize to lung, although the underlying mechanism are still unclear [38,39]. In our study, we combined MPT0G211 with paclitaxel in cell
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b iframe width height src https
2022-05-18
r> Table 1 Descriptive statistics. β = 0.169, p Fig. 3 shows the path from OHIS to health literacy to colonoscopy uptake, and testing the hypotheses revealed similar results compared to the previous model. Namely, OHIS was positively associated with health literacy (H1; β = 0.144, p .0
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br Keywords Follow up Surveillance Symptoms br Introduction
2022-05-18
Keywords: Follow-up, Surveillance, Symptoms Introduction Nonesmall-cell lung cancer (NSCLC) is the leading cause of cancer-related death in the United States and worldwide.1-3 Approximately half of newly diagnosed NSCLC patients present Department of Radiation Oncology, H. Lee Moffitt Can
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br Fig A Identification of potential aptamer candidates Binding
2022-05-17
Fig. 2. (A) Identification of potential aptamer candidates. Binding assays of the selected aptamers, PDGC21 and PDGC45, with the target Oleic acid BGC-823 and the negative cells SGC-7901. (B) The secondary structures of the aptamers PDGC21 and PDGC45 were predicted using the web-based IDT OligoAn
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br antimycotic Thremo The detailed schedule for the di
2022-05-17
antimycotic (Thremo). The detailed schedule for the differentiation of BMDMs is shown in Fig. 2a. Bone marrow cells were extracted from the hind leg and seeded in a culture dish overnight (Day 0). After the floating bone marrow cells were isolated, they were seeded with 20 ng/ ml murine macrophage
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br Whereas survival is improved with palliative systemic
2022-05-17
Whereas survival is improved with palliative systemic treatment, this benefit might be counterbalanced by quality of life concerns. FOLFIRINOX was studied in patients below the age of 76 with ECOG 0–1(median 61) and has significant side effects. However, a recent se-ries showed that 57% of the pat
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